Replication: DNA Building Block Synthesis On Demand
نویسندگان
چکیده
Correct regulation of DNA nucleotide biosynthesis is emerging as a key issue of importance for genome integrity. The fission yeast Spd1 protein can modulate the activity of ribonucleotide reductase (RNR) by at least three different mechanisms. Now a paper reports that Spd1 turnover is linked to ongoing DNA synthesis.
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عنوان ژورنال:
- Current Biology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012